Table 6.
The top 20 most cited original research in HP/GC.
| Rank | Title | First author | Year | Journals | IF | JCR | TC |
|---|---|---|---|---|---|---|---|
| 1 | Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China -: A randomized controlled trial | Wong, BCY | 2004 | JAMA-J. Am. Med. Assoc. | 120.7 | Q1 | 1064 |
| 2 | Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial | Fukase, K | 2008 | Lancet | 168.9 | Q1 | 883 |
| 3 | Global burden of gastric cancer attributable to Helicobacter pylori | Plummer, M | 2015 | Int. J. Cancer | 6.4 | Q1 | 575 |
| 4 | High levels of aberrant DNA methylation in Helicobacter pylori: Infected gastric mucosae and its possible association with gastric cancer risk | Maekita, T | 2006 | Clin. Cancer Res. | 11.5 | Q1 | 498 |
| 5 | Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse | Ohnishi, N | 2008 | Proc. Natl. Acad. Sci. U. S. A. | 11.1 | Q1 | 421 |
| 6 | Progression of chronic atrophic gastritis associated with Helicobacter pylori infection increases risk of gastric cancer | Ohata, H | 2004 | Int. J. Cancer | 6.4 | Q1 | 392 |
| 7 | Activation of β-catenin by carcinogenic Helicobacter pylori | Franco, AT | 2005 | Proc. Natl. Acad. Sci. U. S. A. | 11.1 | Q1 | 381 |
| 8 | Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer | Choi, IJ | 2018 | N. Engl. J. Med. | 158.5 | Q1 | 379 |
| 9 | Fifteen-Year Effects of Helicobacter pylori, Garlic, and Vitamin Treatments on Gastric Cancer Incidence and Mortality | Ma, JL | 2012 | J. Natl. Cancer Inst. | 10.3 | Q1 | 314 |
| 10 | Predicting the development of gastric cancer from combining Helicobacter pylori antibodies and serum pepsinogen status: a prospective endoscopic cohort study | Watabe, H | 2005 | Gut | 24.5 | Q1 | 313 |
| 11 | A new Helicobacter pylori vacuolating cytotoxin determinant, the intermediate region, is associated with gastric cancer | Rhead, JL | 2007 | Gastroenterology | 29.4 | Q1 | 294 |
| 12 | Long-term proton pump inhibitors and risk of gastric cancer development after treatment for Helicobacter pylori: a population-based study | Cheung, KS | 2018 | Gut | 24.5 | Q1 | 271 |
| 13 | Helicobacter pylori infection and gastric atrophy: Risk of adenocarcinoma and squamous-cell carcinoma of the esophagus and adenocarcinoma of the gastric cardia | Ye, WM | 2004 | JNCI-J. Natl. Cancer Inst. | 10.3 | Q1 | 262 |
| 14 | Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivity | Kamangar, F | 2006 | JNCI-J. Natl. Cancer Inst. | 10.3 | Q1 | 253 |
| 15 | Lack of Commensal Flora in Helicobacter pylori-Infected INS-GAS Mice Reduces Gastritis and Delays Intraepithelial Neoplasia | Lofgren, JL | 2011 | Gastroenterology | 29.4 | Q1 | 244 |
| 16 | Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer | Chan, AOO | 2003 | Gut | 24.5 | Q1 | 244 |
| 17 | The benefit of mass eradication of Helicobacter pylori infection: a community-based study of gastric cancer prevention | Lee, YC | 2013 | Gut | 24.5 | Q1 | 240 |
| 18 | Early Helicobacter pylori Eradication Decreases Risk of Gastric Cancer in Patients With Peptic Ulcer Disease | Wu, CY | 2009 | Gastroenterology | 29.4 | Q1 | 217 |
| 19 | Regulation of gastric carcinogenesis by helicobacter pylori virulence factors | Franco, AT | 2008 | Cancer Res. | 11.2 | Q1 | 212 |
| 20 | Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells | Toller, IM | 2011 | Proc. Natl. Acad. Sci. U. S. A. | 11.1 | Q1 | 211 |