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. 2024 Jan 31;13:1343752. doi: 10.3389/fcimb.2023.1343752

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Copyright © 2024 Zhang, Dong, Zheng, Yang, He, Liu and Wei

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fecal metabolome profiling of recipient mice. (A) A bar chart of the metabolite classification overview. (B) PCA plot of feces from sham, vehicle and FFT groups. (C) PLS-DA plot of feces from sham, vehicle and FFT groups. (D) Heatmap of potential biomarkers between the FFT and vehicle groups, with the screening criteria of P < 0.05, |log2FC| >= 0 in univariate analysis and VIP > 1 in multidimensional analysis. (E) Butyric acid levels in the feces of mice treated with FFT or vehicle. (F) metabolite sets enrichment overview. Data are reported as mean ± SEM. Each symbol represents a mouse. *P < 0.05.