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. 2024 Jan 31;14:1250069. doi: 10.3389/fonc.2024.1250069

Table 3.

Analysis of patient and surgical characteristics which may be associated with seroma infection.

Total n=123 No Infection
(n=93, 75.6%)
Infection
(n=30, 24.4%)
p-Value
Sex Male (n=54) 44 10 0.180
Female (n=69) 49 20
Age at Surgery (years) ≤57 (n=62) 48 15 0.878
>57 (n=61) 45 15
Smoking History Yes (n=55) 37 18 0.053
No (n=68) 56 12
Diabetes History Yes (n=15) 10 5 0.389
No (n=108) 83 25
Body Mass Index <30 (n=73) 56 17 0.731
>30 (n=50) 37 13
Radiation Yes (n=107) 80 27 0.573
No (n=16) 13 3
Chemotherapy Yes (n=46) 38 8 0.162
No (n=77) 55 22
Resection Volume (cm3) ≤864 (n=76) 68 8 <0.001
>864(n=47) 25 22
Initial Seroma Volume (cm3)* ≤42 (n=64) 59 5 <0.001
>42 (n=48) 31 17
Intraoperative Drain Placement^ Yes (n=102) 76 26 0.303
No (n=15) 13 2
Flap Coverage Yes (n=55) 38 17 0.130
No (n=68) 55 13
Resection Location Upper Extremity (n=19) 18 1 0.028
Lower Extremity (n=99) 70 29

*Eleven patients experienced seromas which were not officially measured and were diagnosed clinically.

^Intraoperative drain placement was not documented for six patients.

Bold values indicate statistical significance, with a p-value <0.05.