Table 3.
Tissue concentration (μg/g or μg/mL) in Gushi chickens after multiple oral administration of danofloxacin (5 mg/kg BW for 3 consecutive days) (Mean ± SD).
| Tissue/Time | 4 h | 12 h | 24 h | 48 h | 72 h | 120 h |
|---|---|---|---|---|---|---|
| Plasma | 0.170±0.119 | 0.029±0.015 | 0.012±0.004 | 0.006±0.001 | ND | ND |
| Muscle | 0.415±0.258 | 0.183±0.111 | 0.035±0.016 | 0.021±0.005 | ND | ND |
| Skin and Fat | 0.394±0.238 | 0.146±0.105 | 0.065±0.051 | 0.020±0.015 | 0.041±0.033 | 0.021±0.013 |
| Liver | 4.826±3.710 | 0.489±0.272 | 0.171±0.151 | 0.049±0.037 | 0.016±0.013 | 0.016±0.003 |
| Kidney | 3.050±1.690 | 0.276±0.184 | 0.062±0.039 | 0.005 | ND | ND |
| Lung | 1.216±0.825 | 0.205±0.101 | 0.197±0.241 | 0.034±0.028 | 0.018±0.008 | 0.024±0.019 |
| Intestine | 3.157±3.031 | 0.130±0.065 | 0.057±0.068 | 0.009±0.001 | ND | ND |
| Intestinal content | 44.28±20.52 | 1.309±1.299 | 0.168±0.184 | ND | ND | ND |
Time represents the time after the last administration, “ND” indicates “not detected.”