Table 3.

Clinical and Histopathologic Correlative Characteristics

Patient	Disease	Time Since Sclerosis	Degree of Infiltrate	Prednisone	Transcriptomic Group
U1	Unaffected	None	Unaffected	Yes	Unaffected
U2	Unaffected	None	Unaffected	Yes	Unaffected
U3	Unaffected	None	Unaffected	Yes	Unaffected
U4	Unaffected	None	Unaffected	Yes	Unaffected
U5	Unaffected	None	Unaffected	No	Unaffected
U6	Unaffected	None	Unaffected	No	Unaffected
U7	Unaffected	None	Unaffected	Yes	Unaffected
U8	Unaffected	None	Unaffected	No	Unaffected
U9	Unaffected	None	Unaffected	No	Unaffected
A1	Affected	Late	Mild	Yes	1 (fibrotic)
A2	Affected	Early	Moderate	No	5 (fibroinflammatory)
A3	Affected	Late	Mild	Yes	1 (fibrotic)
A4	Affected	Early	Moderate	Yes	4 (fibroinflammatory)
A5	Affected	Late	Mild	Yes	ungrouped
A6	Affected	Late	Mild	Yes	3 (fibroinflammatory)
A7	Affected	Late	Mild	No	3 (fibroinflammatory)
A8	Affected	Early	Mild	Yes	1 (fibrotic)
A9	Affected	Late	Mild	Yes	1 (fibrotic)
A10	Affected	Early	Mild	Yes	2 (fibroinflammatory)
A11	Affected	Early	Mild	Yes	2 (fibroinflammatory)
A12	Affected	Late	Mild	Yes	4 (fibroinflammatory)
A13	Affected	Early	Moderate	No	5 (fibroinflammatory)
A14	Affected	Early	Mild	Yes	2 (fibroinflammatory)
A15	Affected	Late	Moderate	Yes	1 (fibrotic)
A16	Affected	Early	Moderate	No	5 (fibroinflammatory)
A17	Affected	Early	Mild	Yes	3 (fibroinflammatory)

Abbreviations: A, affected; U, unaffected.

The term Early indicates <1 year since sclerosis onset; Late indicates >1 year. For the degree of infiltrate, mild indicates scattered immune cells either in a perivascular or interface pattern and moderate indicates a moderate inflammatory cell infiltrate in the dermis and/or a combination of a perivascular and interface inflammatory cell infiltrate. For prednisone, current use is described.