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Depletion of NK cells in C3H.NK congenic mice does not attenuate development of Lyme arthritis. Groups of C3H.NK (squares) and DBA (circles) mice were treated with phosphate-buffered saline (open symbols) or anti-NK1.1 MAb (closed symbols) and infected with B. burgdorferi as described in Materials and Methods. Ankle diameters were recorded weekly, with measurements pooled from three mice per group. Results are representative of three separate experiments.
