Table 2.
Prevalence of STHs at baseline and 21 months (cluster analysis).
| Prevalence at baseline % (n) 95% CI |
Prevalence at 21 months % (n) 95% CI |
Prevalence risk difference (RD) RD (95% CI) p |
|||||
|---|---|---|---|---|---|---|---|
| IVM-I (N = 372) | IVM-II (N = 458) | IVM-I (N = 505) | IVM-II (N = 674) | IVM-Ib | IVM-IIb | IVM-I vs IVM-IIc | |
| T. trichiura | 19.9 (74) 16.1–24.3 | 21.4 (98) 17.9–25.4 | 11.1 (56) 8.6–14.1 | 12.0 (81) 9.8–14.7 | −0.10 (−0.24 to 0.04) p = 0.23 | −0.04 (−0.29 to 0.22) p = 0.83 | 0.27 (−0.24 to 0.78) p = 0.61 |
| Strongyloides spp. | 4.6 (17) 2.9–7.2 | 7.0 (32) 5.0–9.7 | 1.8 (9) 0.9–3.4 | 1.2 (8) 0.6–2.4 | −0.02 (−0.06 to 0.01) p = 0.20 | −0.07 (−0.14 to −0.01) p = 0.036 | −0.37 (0.92–0.18) p = 0.38 |
| N. americanus | 51.6 (180) 46.5–56.7 | 58.5 (268) 53.4–63.0 | 52.3 (241) 47.9–56.6 | 61.3 (413) 57.5–64.9 | 0.07 (−0.15 to 0.28) p = 0.55 | 0.01 (−0.17 to 0.21) p = 1 | 0.04 (−0.29 to 0.21) p = 0.77 |
| N. americanus MH intensitya | 5.9 (22) 3.9–8.8 | 9.0 (41) 6.7–11.9 | 6.5 (33) 4.7–9.1 | 6.2 (42) 4.6–8.3 | 0.01 (−0.05 to 0.07) p = 0.80 | −0.03 (−0.11 to 0.04) p = 0.42 | −0.40 (−1.00 to 0.20) p = 0.24 |
| A. ceylanicum | 19.9 (74) 16.1–24.3 | 14.4 (66) 11.5–17.9 | 18.8 (95) 15.6–22.5 | 19.6 (132) 16.8–22.8 | −0.01 (−0.09 to 0.05) p = 1 | 0.01 (−0.11 to 0.12) p = 1 | 0.19 (0.72–1.10) p = 1 |
| A. lumbricoides | 0.27 (1) 0.04–1.9 | 1.1 (5) 0.5–2.6 | 0.6 (3) 0.2–1.8 | 1.3 (9) 0.7–2.5 | NA | NA | NA |
p values corrected for multiple testing using the Bonferroni-Holm method. Bold text indicates a statistically significant difference at the alpha level of 0.05.
NA, not applicable due to insufficient observations.
a
Moderate-to-heavy intensity infections.
b
Reference category: baseline timepoint.
c
Reference category: baseline timepoint and IVM-I group.