Table 2.
Patient and tumour characteristics.
| Total |
Cholangiocarcinoma |
Gallbladder cancer |
Ampulla of Vater cancer |
χ2 |
|||||
|---|---|---|---|---|---|---|---|---|---|
| N | Col % | N | Col % | N | Col % | N | Col % | p value∗ | |
| Total | 50,871 | 32,251 | 63.4 | 11,742 | 23.1 | 6,878 | 13.5 | ||
| Age group | |||||||||
| 0-44 | 1,018 | 2 | 656 | 2 | 192 | 1.6 | 170 | 2.5 | |
| 45-54 | 2,914 | 5.7 | 1,783 | 5.5 | 631 | 5.4 | 500 | 7.3 | |
| 55-64 | 7,613 | 15 | 4,708 | 14.6 | 1,754 | 14.9 | 1,151 | 16.7 | |
| 65-74 | 13,846 | 27.2 | 8,621 | 26.7 | 3,224 | 27.5 | 2,001 | 29.1 | |
| 75-84 | 16,532 | 32.5 | 10,495 | 32.5 | 3,951 | 33.6 | 2,086 | 30.3 | 160.786 |
| >84 | 8,948 | 17.6 | 5,988 | 18.6 | 1,990 | 16.9 | 970 | 14.1 | p <0.0001 |
| Sex | |||||||||
| Males | 22,802 | 44.8 | 15,628 | 48.5 | 3,396 | 28.9 | 3,778 | 54.9 | 1,700.000 |
| Females | 28,069 | 55.2 | 16,623 | 51.5 | 8,346 | 71.1 | 3,100 | 45.1 | p <0.0001 |
| Socioeconomic deprivation quintile | |||||||||
| 1 - Least deprived | 9,472 | 18.6 | 6,088 | 18.9 | 2,035 | 17.3 | 1,349 | 19.6 | |
| 2 | 10,591 | 20.8 | 6,761 | 21 | 2,350 | 20 | 1,480 | 21.5 | |
| 3 | 10,536 | 20.7 | 6,680 | 20.7 | 2,384 | 20.3 | 1,472 | 21.4 | |
| 4 | 10,191 | 20 | 6,448 | 20 | 2,418 | 20.6 | 1,325 | 19.3 | 60.828 |
| 5 - Most deprived | 10,081 | 19.8 | 6,274 | 19.5 | 2,555 | 21.8 | 1,252 | 18.2 | p <0.0001 |
| Route to diagnosis | |||||||||
| DCO | 133 | 0.4 | 93 | 0.4 | 34 | 0.4 | 6 | 0.1 | |
| Emergency presentation | 17,781 | 48.1 | 11,718 | 49.7 | 3,985 | 46.4 | 2,078 | 43.1 | |
| GP referral | 8,147 | 22 | 4,839 | 20.5 | 2,111 | 24.6 | 1,197 | 24.8 | |
| Inpatient elective | 1,090 | 2.9 | 654 | 2.8 | 187 | 2.2 | 249 | 5.2 | |
| Other outpatient | 4,170 | 11.3 | 2,440 | 10.4 | 1,074 | 12.5 | 656 | 13.6 | |
| TWW | 4,780 | 12.9 | 3,253 | 13.8 | 959 | 11.2 | 568 | 11.8 | 334.013 |
| Unknown | 883 | 2.4 | 569 | 2.4 | 243 | 2.8 | 71 | 1.5 | p <0.0001 |
| Diagnosis year | |||||||||
| 2001 | 1,896 | 3.7 | 1,165 | 3.6 | 418 | 3.6 | 313 | 4.6 | |
| 2002 | 1,880 | 3.7 | 1,177 | 3.6 | 386 | 3.3 | 317 | 4.6 | |
| 2003 | 1,912 | 3.8 | 1,182 | 3.7 | 416 | 3.5 | 314 | 4.6 | |
| 2004 | 2,051 | 4 | 1,251 | 3.9 | 467 | 4 | 333 | 4.8 | |
| 2005 | 2,169 | 4.3 | 1,365 | 4.2 | 486 | 4.1 | 318 | 4.6 | |
| 2006 | 2,479 | 4.9 | 1,585 | 4.9 | 526 | 4.5 | 368 | 5.4 | |
| 2007 | 2,466 | 4.8 | 1,540 | 4.8 | 551 | 4.7 | 375 | 5.5 | |
| 2008 | 2,676 | 5.3 | 1,733 | 5.4 | 565 | 4.8 | 378 | 5.5 | |
| 2009 | 2,812 | 5.5 | 1,869 | 5.8 | 586 | 5 | 357 | 5.2 | |
| 2010 | 2,985 | 5.9 | 1,953 | 6.1 | 643 | 5.5 | 389 | 5.7 | |
| 2011 | 3,058 | 6 | 1,979 | 6.1 | 685 | 5.8 | 394 | 5.7 | |
| 2012 | 3,104 | 6.1 | 2,000 | 6.2 | 704 | 6 | 400 | 5.8 | |
| 2013 | 3,349 | 6.6 | 2,111 | 6.5 | 783 | 6.7 | 455 | 6.6 | |
| 2014 | 3,324 | 6.5 | 2,061 | 6.4 | 845 | 7.2 | 418 | 6.1 | |
| 2015 | 3,523 | 6.9 | 2,217 | 6.9 | 886 | 7.5 | 420 | 6.1 | |
| 2016 | 3,652 | 7.2 | 2,263 | 7 | 934 | 8 | 455 | 6.6 | |
| 2017 | 3,670 | 7.2 | 2,334 | 7.2 | 910 | 7.7 | 426 | 6.2 | 173.775 |
| 2018 | 3,865 | 7.6 | 2,466 | 7.6 | 951 | 8.1 | 448 | 6.5 | p <0.0001 |
∗p values calculated using Pearson's chi-squared test.
DCO, death certification only; GP, general practitioner; TWW, two week wait.