TABLE 2.
Mean colon scores for adult IL-10-deficient mice populated with defined bacterial flora or SPF flora (without Helicobacter)a
| Flora(s) | Duration of colonization (weeks) | No. of mice examined | Colon scoreb |
|---|---|---|---|
| Six defined bacterial species | 5 | 4 | 0.39 ± 0.1 |
| 9 | 3 | 0.25 ± 0.2 | |
| 13 | 3 | 0.48 ± 0.09 | |
| 20 | 3 | 1.17 ± 0.4 | |
| B. vulgatus | 32 | 4 | 0.58 ± 0.14 |
| SPF (without Helicobacter) | 5–7 | 5 | 2.23 ± 0.18* |
a
Mice were colonized with a mixture of B. vulgatus, S. faecium (Group D), E. coli, P. productus, S. avium and Eubacterium contortum or B. vulgatus alone or were put into a Helicobacter-free SPF environment as described in Materials and Methods.
b
Values are means ± standard errors of the mean. Colon scores are for both the cecum and other colon regions. ∗, significantly different from all other scores (P < 0.05).