Table 2.
Stress Scales | Isoprostane 8 Channel β (SE), p-value |
Isoprostane 2,3 Channel β (SE), p-value |
Isoprostane 6,12 Channel β (SE), p-value |
---|---|---|---|
ACEs | 0.12 (0.06), p = 0.033 | 0.11 (0.04), p = 0.014 | 0.03 (0.07), p = 0.632 |
Financial Stress | 0.02 (0.02), p = 0.904 | −0.02 (0.01), p = 0.882 | −0.05 (0.02), p = 0.007 |
Depression | 0.05 (0.02), p = 0.095 | 0.02 (0.01), p = 0.064 | 0.01 (0.02), p = 0.955 |
Social Support | −0.03 (0.02), p = 0.135 | −0.02 (0.02), p = 0.196 | −0.06 (0.02), p = 0.027 |
Anxiety | 0.03 (0.02), p = 0.188 | 0.01 (0.02), p = 0.415 | 0.01 (0.03), p = 0.953 |
N = 50 pregnant women (25 African American and 25 White). Linear regression models were fit to investigate associations between five prenatal psychosocial stressors and three creatinine-adjusted F2-isoprostane channels. These models were adjusted for cigarette smoking during pregnancy, education level, and race/ethnicity. Pregnant women reporting high levels of ACE had significantly higher i8 channel F2-isoprostane (β = 0.12, SE = 0.06, p = 0.033) and 2,3 channel F2-isoprostane levels (β = 0.11, SE = 0.04, p = 0.014). Two-sample t-tests were completed.