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. 2024 Feb 6;10(3):e25578. doi: 10.1016/j.heliyon.2024.e25578

Table 2.

Association between 5 stress scales and F2-isoprostanes (All).

Stress Scales Isoprostane 8 Channel
β (SE), p-value
Isoprostane 2,3 Channel
β (SE), p-value
Isoprostane 6,12 Channel
β (SE), p-value
ACEs 0.12 (0.06), p = 0.033 0.11 (0.04), p = 0.014 0.03 (0.07), p = 0.632
Financial Stress 0.02 (0.02), p = 0.904 −0.02 (0.01), p = 0.882 −0.05 (0.02), p = 0.007
Depression 0.05 (0.02), p = 0.095 0.02 (0.01), p = 0.064 0.01 (0.02), p = 0.955
Social Support −0.03 (0.02), p = 0.135 −0.02 (0.02), p = 0.196 −0.06 (0.02), p = 0.027
Anxiety 0.03 (0.02), p = 0.188 0.01 (0.02), p = 0.415 0.01 (0.03), p = 0.953

N = 50 pregnant women (25 African American and 25 White). Linear regression models were fit to investigate associations between five prenatal psychosocial stressors and three creatinine-adjusted F2-isoprostane channels. These models were adjusted for cigarette smoking during pregnancy, education level, and race/ethnicity. Pregnant women reporting high levels of ACE had significantly higher i8 channel F2-isoprostane (β = 0.12, SE = 0.06, p = 0.033) and 2,3 channel F2-isoprostane levels (β = 0.11, SE = 0.04, p = 0.014). Two-sample t-tests were completed.