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. Author manuscript; available in PMC: 2024 Oct 1.
Published in final edited form as: Pediatr Clin North Am. 2023 Jul 3;70(5):995–1011. doi: 10.1016/j.pcl.2023.05.010

Table 4.

Case 4 Panel-based testing results

Genotype Results Phenotype Relevant Medication(s) Reference(s)
CYP2D6 *1/*1x2 UM Ondansetron, codeine, tramadol, paroxetine, fluvoxamine 9,31,48
CYP2C19 *1/*2 IM Voriconazole, omeprazole, lansoprazole, pantoprazole, dexlansoprazole, sertraline, escitalopram, citalopram 10,31,51
CYP2C9 *1/*1 NM Celecoxib, flurbiprofen, ibuprofen and lornoxicam 30
CYP3A5 *1/*3 IM Tacrolimus 52
TPMT *1/*1 NM Mercaptopurine 53
NUDT15 *1/*3 IM Mercaptopurine 53

Relevant medication(s) refers to which medications are relevant to the case. Information about genes and results not featured in the case discussion can be found on PharmGKB.

Abbreviations: IM, intermediate metabolizer; NM, normal metabolizer; UM, ultrarapid metabolizer.