TABLE 2.
A 65-Year-Old Woman With Resected Moderately Differentiated Adenocarcinoma of the Pancreatic Head, pT2N1M0 With Negative Margin of Resection, 1 of 15 Lymph Nodes Involved, and no Evidence of Perineural Invasion
| Treatment | Rating | Comments |
|---|---|---|
| Observation | 2 | |
| Chemotherapy alone | ||
| 5-FU | 7 | |
| Gemcitabine | 8 | |
| Multiagent chemotherapy | 4 | |
| Chemoradiation therapy followed by adjuvant chemotherapy | 5 | This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating |
| Chemotherapy followed by chemoradiation therapy followed by chemotherapy | 7 | |
| Chemotherapy × 4–6 mo followed by chemoradiation therapy | 7 | |
| Dose to tumor bed (Gy) | ||
| 45/1.8 | 5 | This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating |
| 50.4/1.8 | 8 | |
| 54/1.8 | 7 | |
| 59.4/1.8 | 3 | |
| RT technique | ||
| AP/PA photons | 3 | |
| 4–5 field photon | 8 | |
| 3-dimensional conformal plan | ||
| IMRT | 8 | |
| RT volume | ||
| Tumor alone | 3 | |
| Tumor + nodal basin | 8 |
Postoperative CA19–9 = 120.
Karnofsky performance status of 80.
Rating Scale: 1, 2, 3 usually not appropriate; 4, 5, 6 may be appropriate; 7, 8, 9 usually appropriate.
AP/PA indicates anterior-posterior/posterior-anterior; 5-FU, 5-fluorouracil; IMRT, intensity-modulated RT; RT, radiation therapy.