TABLE 3.
A 70-Year-Old Man With Resected Poorly differentiated Adenocarcinoma of the Pancreatic Head, pT3N0M0 With a Positive Uncinate Margin of Resection and Postoperative CA19–9 = 140
| Treatment | Rating | Comments |
|---|---|---|
| Observation | 1 | |
| Chemotherapy alone | ||
| 5-FU | 5 | This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating |
| Gemcitabine | 7 | |
| Multiagent chemotherapy | 5 | |
| Chemoradiation therapy followed by adjuvant chemotherapy | 6 | |
| Chemotherapy followed by chemoradiation therapy followed by chemotherapy | 8 | |
| Chemotherapy × 4–6 mo followed by chemoradiation therapy | 8 | |
| Dose to tumor bed (Gy) | ||
| 45/1.8 | 3 | |
| 50.4/1.8 | 7 | |
| 54/1.8 | 8 | |
| 59.4/1.8 | 5 | This option is performed with the use of breathing motion management, close attention to bowel dose, and no small bowel in the field |
| RT technique | ||
| AP/PA photons | 2 | |
| 4–5 field photon 3- | 7 | |
| dimensional conformal plan | ||
| IMRT | 8 | |
| RT volume | ||
| Tumor bed alone | 5 | This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating |
| Tumor bed + nodal basin | 8 |
Karnofsky performance status of 80.
Rating Scale: 1, 2, 3 usually not appropriate; 4, 5, 6 may be appropriate; 7, 8, 9 usually appropriate.
AP/PA indicates anterior-posterior/posterior-anterior; 5-FU, 5-fluorouracil; IMRT, intensity-modulated RT; RT, radiation therapy.