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. Author manuscript; available in PMC: 2024 Feb 14.
Published in final edited form as: Am J Clin Oncol. 2017 Apr;40(2):109–117. doi: 10.1097/COC.0000000000000370

TABLE 3.

A 70-Year-Old Man With Resected Poorly differentiated Adenocarcinoma of the Pancreatic Head, pT3N0M0 With a Positive Uncinate Margin of Resection and Postoperative CA19–9 = 140

Treatment Rating Comments
Observation 1
Chemotherapy alone
 5-FU 5 This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating
 Gemcitabine 7
 Multiagent chemotherapy 5
Chemoradiation therapy followed by adjuvant chemotherapy 6
Chemotherapy followed by chemoradiation therapy followed by chemotherapy 8
Chemotherapy × 4–6 mo followed by chemoradiation therapy 8
Dose to tumor bed (Gy)
 45/1.8 3
 50.4/1.8 7
 54/1.8 8
 59.4/1.8 5 This option is performed with the use of breathing motion management, close attention to bowel dose, and no small bowel in the field
RT technique
 AP/PA photons 2
 4–5 field photon 3- 7
  dimensional conformal plan
 IMRT 8
RT volume
 Tumor bed alone 5 This option may be appropriate but there was disagreement among panel members on the appropriateness rating as defined by the panel’s median rating
 Tumor bed + nodal basin 8

Karnofsky performance status of 80.

Rating Scale: 1, 2, 3 usually not appropriate; 4, 5, 6 may be appropriate; 7, 8, 9 usually appropriate.

AP/PA indicates anterior-posterior/posterior-anterior; 5-FU, 5-fluorouracil; IMRT, intensity-modulated RT; RT, radiation therapy.