TABLE 2.

Ng circularity measure.

Region	Control	Intermediate AD	P value	Significance
Entorhinal cortex	0.47 ± 0.03	0.53 ± 0.02	0.07	ns
Subiculum	0.49 ± 0.03	0.52 ± 0.02	0.88	ns
CA1	0.67 ± 0.05	0.64 ± 0.03	0.6	ns
CA2	0.37 ± 0.03	0.67 ± 0.04	0.0007	***
CA3	0.40 ± 0.05	0.54 ± 0.02	0.013	*
Dentate gyrus	0.77 ± 0.04	0.75 ± 0.05	0.95	ns

Note. t test for each ROI, mean ± SD, P value, and significance.

Abbreviations: AD, Alzheimer's disease; CA, cornu ammonis; Ng, neurogranin; ns, not significant; ROI, region of interest; SD, standard deviation.

^* P < 0.05.

^*** P < 0.001.