TABLE 1.
Demographic Characteristics of LonGenity Cohort at Baseline by MCR Status
| Characteristic | No MCR, n = 481a | Prevalent MCR, n = 84 | Incident MCR, n = 135 |
|---|---|---|---|
| Age, mean yr ± SD | 74.7 ± 6.4 | 75.7 ± 6.9 | 75.3 ± 6.0 |
| Women, n (%) | 286 (59.5) | 46 (54.8) | 73 (54.1) |
| Education, mean yr ± SD | 17.68 ± 2.73 | 17.50 ± 3.26 | 17.69 ± 2.83 |
| Frailty index, mean ± SD | 0.14 ± 0.07 | 0.22 ± 0.09 | 0.17 ± 0.07 |
| Medical illnesses | |||
| Global health score, mean ± SDb | 1.08 ± 0.97 | 1.77 ± 1.18 | 1.45 ± 1.07 |
| Hypertension, % | 37.7 | 62 | 58.1 |
| Myocardial infarction, % | 4.4 | 3.6 | 9.7 |
| Congestive heart failure, % | 0.4 | 1.2 | 1.5 |
| Stroke, % | 1.7 | 6 | 5.2 |
| Cancer, % | 34.9 | 31 | 33.3 |
| Diabetes, % | 6 | 15.5 | 11.1 |
| Chronic lung disease, % | 2.5 | 3.6 | 2.2 |
| Arthritis, % | 38.6 | 56.6 | 40.6 |
| Parkinson disease, % | 1.3 | 2.4 | 0 |
| Depression, % | 18.5 | 32.1 | 24.1 |
| Cognitive tests, mean ± SD | |||
| FCSRT free recall | 33.70 ± 5.34 | 34.00 ± 4.86 | 33.76 ± 4.91 |
| DSST | 61.38 ± 14.34 | 58.29 ± 12.57 | 60.48 ± 13.73 |
a
No MCR: participants who were free from MCR at baseline as well as throughout the study follow-up.
b
Presence or absence of physician-diagnosed depression, diabetes, heart failure, hypertension, myocardial infarction, strokes, Parkinson disease, ohronic obstructive lung disease, and arthritis was used to calculate a global health score (range = 0–9) as previously described.37
Abbreviation: DSST = Digit Symbol Substitution Test; FCSRT = Free and Cued Selective Reminding Test; MCR = motoric cognitive risk synrome; SD = standard deviation.