Table 4.
Effect of the ethanolic bark extract (EBE) and its successive fractions (1 & 2%) of Thespesia populnea (L.) on wound area contraction in circular excision wound model (n = 10)
| Groups | Dose (%) | Wound contraction (%) | |||||
|---|---|---|---|---|---|---|---|
| Day 2 | Day 5 | Day 7 | Day 11 | Day 14 | |||
| G(1) | Normal Control | – | – | – | – | – | – |
| G(2) | Positive control (untreated) | – | 7.31C | 14.8 g | 48.6C | 62.1 C | 71.92d |
| G(3) | Vehicle hydrogel base | – | 9.13 b | 27.54 d | 36.60d | 69.24 b | 74.8C |
| G(4) | EBE | 1 | 8.56 bC | 21.60 f | 54.20c | 82.98a | 90.10a |
| G(5) | Pet-B | 1 | 7.22 c | 30.13 d | 57.96 c | 83.73 a | 94.55 b |
| G(6) | Met-B | 1 | 9.11b | 31.48 d | 53.80 c | 81.58 b | 87.18 b |
| G(7) | Etac-B | 1 | 8.54 bc | 24.70 de | 60.40 b | 82.14 b | 91.43 a |
| G(8) | But-B | 1 | 9.76b | 16.10 g | 37.71 d | 53.97 d | 72.94 d |
| G(9) | EBE | 2 | 15.40a | 25.94 de | 65.60a | 85.90a | 93.30b |
| G(10) | Pet-B | 2 | 9.58 b | 35.42c | 62.05 ab | 83.70a | 95.10 b |
| G(11) | Met-B | 2 | 9.65 b | 39.30 b | 61.5 b | 79.23a | 87.45a |
| G(12) | Etac-B | 2 | 9.78 b | 44.30a | 63.77ab | 84.87 a | 93.10b |
| G(13) | But-B | 2 | 10.95 b | 24.73e | 39.7 d | 54.84 d | 73.24C |
Values are expressed as mean, values with different superscript letters (a-g) in the same column at the same interval differ significantly (P < 0.05), Normal control: healthy group, Positive control: untreated group, Vehicle: hydrogel base
Pet-B petroleum ether, Met-B methylene chloride, Etac-B ethyl acetate, But-B butanol fractions