Table 4.
mQTLs and disease associated, according to phenoscanner
| ID_cg | Gene of cg | Chr | Position | rs | Gene of rs | Chr | Position | A1 | A2 | Disease | Beta | P-val | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| cg06378491 | MAP4K2 | 11 | 64,564,012 | rs74374453 | AP005273.1 | 11 | 64,271,540 | cis | A | G | Insulin-like growth factor 1 | 4.96E-02 | ||
| Gestational diabetes only | -0.086 | 2.99E-03 | ||||||||||||
| Self-reported type 1 diabetes | -0.0007011 | 4.28E-02 | ||||||||||||
| cg14020176 | SLC9A3R1 | 17 | 72,764,985 | rs2385067 | TMEM104 | 17 | 72,810,070 | cis | A | G | Type II diabetes | -0.195 | 4.62E-04 | |
| rs652963 | QSER1 | 11 | 32,911,737 | trans | T | C | Illnesses of siblings: diabetes | -0.002764 | 7.23E-03 | |||||
| Type II diabetes | -0.036 | 2.80E-02 | ||||||||||||
| cg14870271 | LGALS3BP | 17 | 76,976,010 | rs117549034 | USP36 | 17 | 76,826,416 | cis | C | T | Parkinson Disease | -0.02651 | 2.82E-06 | |
| Diabetes mellitus in pregnancy | -0.0004308 | 1.18E-02 | ||||||||||||
| Started insulin within one year diagnosis of diabetes | 0.04261 | 1.40E-02 | ||||||||||||
| Eye problems or disorders: diabetes related eye disease | -0.005733 | 4.11E-02 | ||||||||||||
| cg22650271 | SYNGR1 | 22 | 39,760,165 | rs5757582 | AL031590.1 | 22 | 39,661,032 | cis | A | C | Rheumatoid arthritis | -0.06188 | 1.90E-05 | |
| Crohn’s disease | 0.000472 | 4.76E-04 | ||||||||||||
| Type II diabetes adjusted for BMI | 0.038 | 9.40E-03 | ||||||||||||
| rs7289325 | PDGFB | 39,642,577 | cis | A | T | Started insulin within one year diagnosis of diabetes | -0.009563 | 1.25E-02 | ||||||
| Gestational diabetes only | 0.01211 | 4.44E-02 | ||||||||||||
| rs742402 | AL031590.1 | 39,659,487 | cis | A | G | High cholesterol | -0.002935 | 4.90E-04 | ||||||
| Crohns disease | -0.0004341 | 2.30E-03 | ||||||||||||
| Rheumatoid arthritis | 0.06766 | 1.70E-05 | ||||||||||||
| Type II diabetes adjusted for BMI | -0.04 | 9.50E-03 | ||||||||||||
| Illnesses of mother: diabetes | -0.001557 | 4.31E-02 | ||||||||||||
| Medication for cholesterol, blood pressure or diabetes: none of the above | 0.003574 | 4.64E-02 | ||||||||||||
| rs9611137 | SCUBE1 | 39,682,445 | cis | C | T | Crohn’s disease | -0.2224 | 3.76E-05 | ||||||
| Inflammatory bowel disease | -0.152 | 8.48E-05 | ||||||||||||
| High cholesterol | -0.00366 | 2.90E-02 | ||||||||||||
| Medication for cholesterol, blood pressure or diabetes: cholesterol lowering medication | -0.00794 | 1.33E-02 | ||||||||||||
| Type II diabetes adjusted for BMI | -0.071 | 2.90E-02 |