Table 2.

Percent methylation of the 4 CpGs of the 1st enhancer of CDH1 gene in ileal mucosa and PBMC

	Crohn Disease N = 21	Controls N = 16	P value
Ileal mucosa:
CpG-4414	34 ± 12	26 ± 12	0.02
CpG-4512	58 ± 11	48 ± 11	0.01
CpG-4584	33 ± 11	26 ± 11	0.03
CpG-4628	56 ± 17	42 ± 17	0.01
Average CpGs	45 ± 17	35 ± 17	< 0.001
PBMC:
CpG-4414	29 ± 5	31 ± 4	NS
CpG-4512	46 ± 4	45 ± 5	NS
CpG-4584	30 ± 4	32 ± 4	NS
CpG-4628	43 ± 4	43 ± 4	NS
Average CpGs	37 ± 9	38 ± 4	NS

Mean (± SD); decimal values rounded to the nearest integer