Figure 1. Association of SNPs associated with mammographic density in women of European ancestry with MD and breast cancer risk in Asian women.

Associations for SNPs reported to be associated with a) Dense area or volume, b) Percent dense area or volume, c) Non-dense area, in women of European ancestry with area and volumetric densities, and breast cancer risk in Asian women. Associations for SNPs excluded from the breast cancer risk analysis are not available and marked ‘na.’ in the forest plots.

Note: SNPs in each section a), b) and c), are ordered by Beta values of the respective reported association phenotype. For example, forest plots in a) are ordered according to Beta values for dense area in this study. SNPs associated with volumetric densities are annotated for reference. Area measurements were performed using STRATUS and volumetric density measurements using Volpara^™.

* SNP reported to be associated with both dense area or percent dense area; † SNP is associated with dense volume; ‡ SNP is associated with non-dense area and percent dense area; § SNP is associated with percent dense volume; Direction of association with MD in this study is not consistent with reported association in women of European ancestry.