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. 2024 Jan 9;15(2):e02372-23. doi: 10.1128/mbio.02372-23

TABLE 2.

Incidence of binary clinical outcomes after H1N1 challenge

Unvaccinated N (%) Vaccinated N (%) P-valuea
Total N 37 37
MMIDb 30 (81%) 18 (49%) 0.0068
Fluc 34 (92%) 22 (59%) 0.0023
Symptomsd 35 (95%) 27 (73%) 0.0242
Sheddinge 30 (81%) 23 (62%) 0.1208
a

P-values from Fisher’s exact tests with no adjustment for multiple comparisons. P < 0.05 considered statistically significant.

b

MMID defined as at least one influenza symptom plus at least 1 day of viral shedding.

c

Flu defined as at least one influenza symptom, plus either at least 1 day of viral shedding or a greater than fourfold increase in either hemagglutinin inhibition titers or neuraminidase inhibition titers.

d

Symptoms defined as presence of at least one influenza symptom.

e

Shedding defined as presence of shedding on at least 1 day.