TABLE 2.
Incidence of binary clinical outcomes after H1N1 challenge
| Unvaccinated N (%) | Vaccinated N (%) | P-valuea | |
|---|---|---|---|
| Total N | 37 | 37 | |
| MMIDb | 30 (81%) | 18 (49%) | 0.0068 |
| Fluc | 34 (92%) | 22 (59%) | 0.0023 |
| Symptomsd | 35 (95%) | 27 (73%) | 0.0242 |
| Sheddinge | 30 (81%) | 23 (62%) | 0.1208 |
P-values from Fisher’s exact tests with no adjustment for multiple comparisons. P < 0.05 considered statistically significant.
MMID defined as at least one influenza symptom plus at least 1 day of viral shedding.
Flu defined as at least one influenza symptom, plus either at least 1 day of viral shedding or a greater than fourfold increase in either hemagglutinin inhibition titers or neuraminidase inhibition titers.
Symptoms defined as presence of at least one influenza symptom.
Shedding defined as presence of shedding on at least 1 day.