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. 2024 Jan 9;15(2):e02372-23. doi: 10.1128/mbio.02372-23

TABLE 3.

Median antibody titers before H1N1 challenge at day −1 grouped by participant shedding statusc,d,e

Non-shedders 1-day shedders Long-sheddersa P-valueb
Total N 21 19 34
Serum HAI 80 80 20 0.0008
Serum NAI 160 160 80 0.0079
Serum HA IgG 447,088 402,805 290,263 0.0008
Serum HA stalk IgG 187,087 196,786 130,218 0.0739
Serum NA 5,967 4,556 3,879 0.1633
Nasal HA IgA 953 790 467 0.0273
Nasal HA stalk IgA 586 1,215 790 0.2374
Nasal NA IgA 36 35 35 0.8814
a

Long-shedders defined as those with 2 or more days of shedding.

b

P-values from Kruskal–Wallis tests (pairwise Wilcoxon rank sum tests adjusted by the Benjamini–Hochberg method performed when P-value <0.05, results available in supplemental). P < 0.05 considered statistically significant.

c

Symptoms defined as presence of at least one influenza symptom.

d

Shedding defined as presence of shedding on at least 1 day.

e

HAI, hemagglutinin inhibition; NAI, neuraminidase inhibition; HA, hemagglutinin; NA, neuraminidase.