TABLE 2.
SR pattern azoles a
| ID | Patient ID | Date collected | Flu MIC value | Mutations PDR1 | Treatment c |
|---|---|---|---|---|---|
| CAS10-2614_S20 | 22 | 27-Oct-10 | 8 | Mica b | |
| CAS12-3684_S68 | 22 | 21-Nov-11 | 4 | Mica | |
| CAS13-4530_S71 | 22 | 1-Nov-12 | 16 | Mica; Flu; Ampho | |
| CAS13-4778_S42 g | 22 | 13-Mar-13 | Mica; Flu; Ampho | ||
| CAS13-5011_S55 | 22 | 16-Jun-13 | 64 | p.Glu714Asp d | Mica; Flu |
| CAS08_0124_S32 | 1 | 28-May-08 | 32 | ||
| CAS12-4416_S11 | 1 | 3-Nov-12 | 64 | Flu; Mica | |
| CAS12-4158_S70 | 21 | 7-Jul-12 | 4 | None | |
| CAS13-4494_S47 | 21 | 19-Nov-12 | 8 | Flu | |
| CAS14-5293_S38 | 21 | 24-Nov-13 | 64 | Mica; Flu | |
| CAS14-5468_S77 | 21 | 10-Feb-14 | 32 | Mica; Flu | |
| CAS11-3025_S92 | 8 | 17-Mar-11 | 8 | Mica | |
| CAS12-3743_S58 | 8 | 3-Jan-12 | 128 | p.Gly1079Glu f | Flu; Mica |
| CAS10-2486_S79 | 15 | 28-Aug-10 | 4 | Flu | |
| CAS10-2596_S8 | 15 | 17-Oct-10 | 64 | p.Gly1099Ser | Flu; Mica |
| CAS11-3232_S57 | 15 | 16-May-11 | 8 | Mica | |
| CAS09-1541_S6 | 18 | 16-Sep-09 | 8 | Unknown | |
| CAS10-2227_S31 | 18 | 26-May-10 | 64 | p.Asn1091Asp d | Unknown |
| CAS09-1361_S41 | 19 | 19-Jul-09 | 8 | Unknown | |
| CAS09-1513_S89 | 19 | 27-Aug-09 | 256 | p.Arg376Gln e | Unknown |
a
Shaded MIC values represent resistant isolates. Patient IDs in bold font represent patients in common with SR pattern for echinocandins.
b
Mica = micafungin, Flu = fluconazole, Ampho = amphotericin B.
c
Patient received systemic antifungal medication to treat candidemia on or after positive culture date.
d
Previously reported by Won E. et al 2021.
e
Change in the same position R376W previously reported by Ferrari et al 2009 (43).
f
Change in the same position G1079R previously reported by Won E. et al 2021.
g
Fluconazole MIC value missing for this isolate.