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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: Mol Genet Metab. 2023 Sep 8;140(3):107696. doi: 10.1016/j.ymgme.2023.107696

Table 2:

Sample sizes required for detecting differences on HRQoL in UCDs based on data generated by this study.

Total n required in a parallel group design to detect a mean difference of
Mean score SD 5 10
PedsQL Child Report
Physical Health Summary Score 79.8 17.9 406 104
Psychosocial Health Summary Score 72.7 17.6 392 100
PedsQL Parent Report
Physical Health Summary Score 76.4 24.2 736 186
Psychosocial Health Summary Score 73.0 18.5 432 110
SF-36v2
Physical Component 48.6 12.3 192 50
Mental Component 46.3 12.2 190 50