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. 2011 May 5;129(3):153–164. doi: 10.1590/S1516-31802011000300006

Table 5. Clinical details and characteristics of patients admitted due to adverse drug reactions and the suspected medicines (ADR).

Adverse drug reactions Indication for the medicine Medicine(s) used Suspected medicine(s) Age (years) Sex Severity Duration of admission (days)
Dystonia Malaria, enteric fever* Cefixime, amodiaquine/artesunate, paracetamol Amodiaquine, artesunate, cefixime 12 Male Moderate 4
Hypothermia Malaria, enteric fever* Cefixime, amodiaquine/artesunate, paracetamol Amodiaquine, artesunate, cefixime 12 Male Moderate 4
Electrolyte disturbance Status asthmaticus* Prednisolone, salbutamol, erythromycin Prednisolone 6 Female Moderate 14
Hyperglycemia Status asthmaticus* Prednisolone, salbutamol, erythromycin Prednisolone 6 Female Moderate 14
Erythema multiforme Generalized seizure* Phenobarbitone Phenobarbitone 6 Male Severe 8
Erythema multiforme URTI, malaria§ Sulfadoxine/pyrimethamine, co-trimoxazole, paracetamol Sulfadoxine/pyrimethamine, co-trimoxazole 10 Male Severe 21
Erythema multiforme URTI|| Co-trimoxazole Co-trimoxazole 12 Male Severe 28
Erythema multiforme URTI|| Co-trimoxazole, ampicillin Co-trimoxazole, ampicillin 8 Female Severe 18
Erythema multiforme URTI, malaria§ Co-trimoxazole, chloroquine, paracetamol Co-trimoxazole 10 Male Severe 20
Macular and morbiliform rash URTI Ampicillin Ampicillin 2 Female Moderate 7
Macular and morbiliform rash Abdominal pain§ Albendazole Albendazole 10 Male Moderate 10
Ileus Diarrhea Loperamide, co-trimoxazole, chloroquine Loperamide 3 Male Moderate 7
Stevens-Johnson syndrome Malaria, enteric fever§ Ampicillin, co-trimoxazole, sulfadoxine/pyrimethamine, ibuprofen Ampicillin, Co-trimoxazole, sulfadoxine/pyrimethamine 10 Male Fatal Died 10 days later
Stevens-Johnson syndrome Malaria, URTI§ Ampicillin, co-trimoxazole, sulfadoxine/pyrimethamine Ampicillin, Co-trimoxazole, sulfadoxine/pyrimethamine 12 Male Fatal Died 5 days later
*

Medicine prescribed at the Lagos State University Teaching Hospital outpatient clinic;

a patient who presented with two types of suspected adverse drug reactions (dystonia and hypothermia) to more than one medicine;

a patient who presented with two types of suspected adverse drug reactions (electrolyte disturbances and hyperglycemia) to a single suspected medicine;

§

self-medicated medicine (medicine not prescribed by a doctor);

||

medicine prescribed at a primary healthcare center;

medicine prescribed by a general practitioner. URTI = upper respiratory tract infection.