Skip to main content
. 2011 May 5;129(3):153–164. doi: 10.1590/S1516-31802011000300006

Table 6. Clinical details and characteristics of inpatients who experienced adverse drug reactions (ADR) and the suspected medicines.

Adverse drug reactions Admission diagnosis Medicine(s) administered Suspected medicine(s) Age Sex Severity Duration of admission
Anaphylactic shock Retinoblastoma Vincristine, etoposide, allopurinol Etoposide 3.5 years Male Severe 8 weeks
Anaphylactic shock Septicemia Ceftriaxone, gentamicin, artemether/lumefantrine Ceftriaxone 8.5 years Female Severe 3 weeks
Anemia Recurrent generalized seizure Carbamazepine, artemether/lumefantrine Carbamazepine 4 years Male Severe 4 weeks
Angioneurotic edema Lobar pneumonia Amodiaquine, cefuroxime, gentamicin Amodiaquine 10 years Female Severe 4 weeks
Tachycardia Acute severe asthma Salbutamol, prednisolone, erythromycin Salbutamol 10.5 years Male Moderate 1 week
Constipation Painful crises in a sickle cell anemic patient Tramadol, gentamicin, cefuroxime, artemether/lumefantrine Tramadol 6 years Female Moderate 2 weeks
Constipation Amoebiasis Metronidazole, chloroquine, amoxicillin Metronidazole, amoxicillin 8 years Male Moderate 2 weeks
Constipation Osteomyelitis Pentazocine, ibuprofen, vancomycin, ciprofloxacin Pentazocine 6 years Female* Moderate 6 weeks
Sedation Osteomyelitis Pentazocine, ibuprofen, vancomycin, ciprofloxacin Pentazocine 6 years Female* Moderate 6 weeks
Diarrhea Presumed sepsis Amoxicillin/clavulanic acid, gentamicin, paracetamol Amoxicillin/clavulanic acid 3 years Female Moderate 2 weeks
Dystonia Malaria Chloroquine, promethazine, paracetamol Promethazine 12 years Male Moderate 1 week
Erythema multiforme Cerebral abscess Cefotaxime, Ampicillin, phenobarbitone Ampicillin, phenobarbitone 0.5 years Male Severe 6 months
Erythema multiforme Presumed sepsis Ciprofloxacin, Cefixime Cefixime 9 years Male* Severe 4 weeks
Seizure Presumed sepsis Ciprofloxacin, Cefixime Cefixime 9 years Male* Severe 4 weeks
Electrolyte disturbances Nephrotic syndrome Frusemide, potassium supplement, prednisolone, ciprofloxacin Frusemide, prednisolone 11 years Male Moderate 4 weeks
Electrolyte disturbances Congestive cardiac failure Frusemide, potassium supplement (under dosage), crystalline penicillin Frusemide 10 years Male* Moderate 2 weeks
Ileus Congestive cardiac failure Frusemide, potassium supplement (under dosage), crystalline penicillin Frusemide 10 years Male* Moderate 2 weeks
Hemolysis Malaria Co-trimoxazole artemether/lumefantrine, paracetamol Co-trimoxazole 10 years Male Severe 4 weeks
Transient loss of vision Malaria Quinine, paracetamol Quinine 6 years Male Moderate 4 weeks
Macular and morbiliform rash Presumed sepsis Cefotaxime, gentamicin Cefotaxime 5 days Male Moderate 3 weeks
Pustular rash Sepsis Vancomycin, gentamicin Vancomycin 3 days Female Moderate 2 weeks
Pustular rash Sepsis Vancomycin, gentamicin Vancomycin 2 days Female Moderate 2 weeks
Pustular rash Sepsis Vancomycin, gentamicin Vancomycin 2 days Female Moderate 4 weeks
Pustular rash Sepsis Vancomycin, gentamicin Vancomycin 4 days Male Moderate 4 weeks
Red man syndrome Osteomyelitis Vancomycin, chloramphenicol Vancomycin 3 years Male Severe 6 weeks
Red man syndrome Osteomyelitis Vancomycin, chloramphenicol Vancomycin 6 years Female Severe 6 weeks
*

Patients manifesting two types of adverse drug reactions to a single medicine (pentazocine, cefixime or frusemide).