Table 6. Clinical details and characteristics of inpatients who experienced adverse drug reactions (ADR) and the suspected medicines.
Adverse drug reactions | Admission diagnosis | Medicine(s) administered | Suspected medicine(s) | Age | Sex | Severity | Duration of admission |
---|---|---|---|---|---|---|---|
Anaphylactic shock | Retinoblastoma | Vincristine, etoposide, allopurinol | Etoposide | 3.5 years | Male | Severe | 8 weeks |
Anaphylactic shock | Septicemia | Ceftriaxone, gentamicin, artemether/lumefantrine | Ceftriaxone | 8.5 years | Female | Severe | 3 weeks |
Anemia | Recurrent generalized seizure | Carbamazepine, artemether/lumefantrine | Carbamazepine | 4 years | Male | Severe | 4 weeks |
Angioneurotic edema | Lobar pneumonia | Amodiaquine, cefuroxime, gentamicin | Amodiaquine | 10 years | Female | Severe | 4 weeks |
Tachycardia | Acute severe asthma | Salbutamol, prednisolone, erythromycin | Salbutamol | 10.5 years | Male | Moderate | 1 week |
Constipation | Painful crises in a sickle cell anemic patient | Tramadol, gentamicin, cefuroxime, artemether/lumefantrine | Tramadol | 6 years | Female | Moderate | 2 weeks |
Constipation | Amoebiasis | Metronidazole, chloroquine, amoxicillin | Metronidazole, amoxicillin | 8 years | Male | Moderate | 2 weeks |
Constipation | Osteomyelitis | Pentazocine, ibuprofen, vancomycin, ciprofloxacin | Pentazocine | 6 years | Female* | Moderate | 6 weeks |
Sedation | Osteomyelitis | Pentazocine, ibuprofen, vancomycin, ciprofloxacin | Pentazocine | 6 years | Female* | Moderate | 6 weeks |
Diarrhea | Presumed sepsis | Amoxicillin/clavulanic acid, gentamicin, paracetamol | Amoxicillin/clavulanic acid | 3 years | Female | Moderate | 2 weeks |
Dystonia | Malaria | Chloroquine, promethazine, paracetamol | Promethazine | 12 years | Male | Moderate | 1 week |
Erythema multiforme | Cerebral abscess | Cefotaxime, Ampicillin, phenobarbitone | Ampicillin, phenobarbitone | 0.5 years | Male | Severe | 6 months |
Erythema multiforme | Presumed sepsis | Ciprofloxacin, Cefixime | Cefixime | 9 years | Male* | Severe | 4 weeks |
Seizure | Presumed sepsis | Ciprofloxacin, Cefixime | Cefixime | 9 years | Male* | Severe | 4 weeks |
Electrolyte disturbances | Nephrotic syndrome | Frusemide, potassium supplement, prednisolone, ciprofloxacin | Frusemide, prednisolone | 11 years | Male | Moderate | 4 weeks |
Electrolyte disturbances | Congestive cardiac failure | Frusemide, potassium supplement (under dosage), crystalline penicillin | Frusemide | 10 years | Male* | Moderate | 2 weeks |
Ileus | Congestive cardiac failure | Frusemide, potassium supplement (under dosage), crystalline penicillin | Frusemide | 10 years | Male* | Moderate | 2 weeks |
Hemolysis | Malaria | Co-trimoxazole artemether/lumefantrine, paracetamol | Co-trimoxazole | 10 years | Male | Severe | 4 weeks |
Transient loss of vision | Malaria | Quinine, paracetamol | Quinine | 6 years | Male | Moderate | 4 weeks |
Macular and morbiliform rash | Presumed sepsis | Cefotaxime, gentamicin | Cefotaxime | 5 days | Male | Moderate | 3 weeks |
Pustular rash | Sepsis | Vancomycin, gentamicin | Vancomycin | 3 days | Female | Moderate | 2 weeks |
Pustular rash | Sepsis | Vancomycin, gentamicin | Vancomycin | 2 days | Female | Moderate | 2 weeks |
Pustular rash | Sepsis | Vancomycin, gentamicin | Vancomycin | 2 days | Female | Moderate | 4 weeks |
Pustular rash | Sepsis | Vancomycin, gentamicin | Vancomycin | 4 days | Male | Moderate | 4 weeks |
Red man syndrome | Osteomyelitis | Vancomycin, chloramphenicol | Vancomycin | 3 years | Male | Severe | 6 weeks |
Red man syndrome | Osteomyelitis | Vancomycin, chloramphenicol | Vancomycin | 6 years | Female | Severe | 6 weeks |
Patients manifesting two types of adverse drug reactions to a single medicine (pentazocine, cefixime or frusemide).