Table 1. Correlation between PROX1 or α-SMA expression and patients’ clinicopathological characteristics.
Clinical characteristics | PROX1 expression | P-value | α-SMA expression | P-value | ||
High (n = 116) | Low (n = 48) | High (n = 130) | Low (n = 34) | |||
Gender | 0.70 | 0.60 | ||||
Male | 57 | 22 | 64 | 15 | ||
Female | 59 | 26 | 66 | 19 | ||
Mean age | 66.0 | 62.9 | 0.16 | 65.4 | 63.9 | 0.079 |
Location | 0.29 | 0.70 | ||||
Right side | 44 | 14 | 45 | 13 | ||
Left side | 72 | 34 | 85 | 21 | ||
Size | <0.001 | <0.001 | ||||
≤5 cm | 44 | 41 | 55 | 30 | ||
>5 cm | 72 | 7 | 75 | 4 | ||
Histology type | <0.001 | <0.001 | ||||
Well | 0 | 10 | 0 | 10 | ||
Moderate | 100 | 35 | 114 | 21 | ||
High or mucinous | 16 | 3 | 16 | 3 | ||
Serosal invasion | <0.001 | <0.001 | ||||
Positive | 111 | 20 | 123 | 8 | ||
Negative | 5 | 28 | 7 | 26 | ||
Lymphatic invasion | 0.002 | 0.004 | ||||
Positive | 65 | 14 | 70 | 9 | ||
Negative | 51 | 34 | 60 | 25 | ||
Venous invasion | 0.089 | 0.11 | ||||
Positive | 53 | 15 | 58 | 10 | ||
Negative | 63 | 33 | 62 | 24 | ||
Lymph node metastasis | <0.001 | <0.001 | ||||
Positive | 69 | 9 | 76 | 2 | ||
Negative | 47 | 39 | 54 | 32 | ||
Distant metastasis | 0.016 | 0.055 | ||||
Positive | 13 | 0 | 13 | 0 | ||
Negative | 103 | 48 | 117 | 34 | ||
Stage | ||||||
I | 0 | 27 | <0.001 | 2 | 25 | <0.001 |
II | 45 | 12 | 50 | 7 | ||
III | 58 | 9 | 65 | 2 | ||
IV | 13 | 0 | 13 | 0 |