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. 2024 Feb 16;10(7):eadk6714. doi: 10.1126/sciadv.adk6714

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Fig. 1. — (A) Schematic illustration of a wireless multi-sensing system integrated into a single-use cell bag, which can monitor the cell culture environment in real-time for continuous 30 days. Sensing data are wirelessly transmitted to a mobile device for feedback-based control of culture parameters. (B) Flow chart capturing the stem cell culture process using the smart bioreactor system. (C) Key features of the multisensory-integrated platform, including soft, thin-film sensors, interconnects, and a circuit connector for a connection with a wireless circuit. (D and E) Photos showing a completed cell culture platform using a petri dish with the sensor package (D) and a set of different scale cell bags with integrated thin-film sensors for real-time, continuous, in situ monitoring of stem cell culture in a 2-liter volume solution (E).