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. 2024 Jan 30;9(1):e1222. doi: 10.1002/lio2.1222

TABLE 1.

Grading of histologic indexes for cartilage regeneration.

Histologic index Grade 0 Grade 1 Grade 2 Grade 3
Tissue morphology

Fibrous tissue

(Poor quality repair tissue, characterizedby collagen fibers throughout the tissue and the presence of blood vessels)

Fibrocartilage

(Collagen fibers can be seen throughout the immature cartilage tissue)

Mixed hyaline and fibrocartilage

Hyaline cartilage

(Good‐qualityrepair tissue, represented by homogeneous (glass‐like) tissue with no obvious collagen fibers)

Cell Morphology Mostly spindle‐shaped cells Both spindle‐shaped (dominant) and round/oval cells Both spindle‐shaped and round/oval cells (dominant) Mostly round/oval cells
Lacuna formation (%) <25 25–50 51–75 >75
New vascularization (%) <25 25–50 51–75 >75
Inflammation None Scant Moderate Abundant