TABLE 1.
Invasion of epithelial and endothelial cells by P. gingivalis A7436
| Cell type | Bacteria adhering and invading (%)a | Invasion efficiency (%)b |
|---|---|---|
| KB epithelial | 1.1 ± 0.3 | 0.01 ± 0.003 |
| Bovine aortic endothelial | 0.12 ± 0.02 | 0.1 ± 0.03 |
| Bovine heart endothelial | 0.35 ± 0.04 | 0.3 ± 0.04 |
| Human umbilical vein endothelial | 0.5 ± 0.06 | 0.2 ± 0.05 |
a
Defined as the percentage of CFU input that bound to epithelial or endothelial cells; represents both bacteria adhering and invading. Values are the means of triplicate independent determinations from a typical experiment ± standard deviations.
b
Percentage of the inoculum (P. gingivalis) protected from metronidazole killing after the infection period relative to the number of bacteria adhering. Values are the means of triplicate independent determinations from a typical experiment ± standard deviations.