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JAK2 VAF (%) in 255 MPN patients separated according to SVT chronology. This box plot plus jitter shows JAK2 VAF distribution according to SVT chronology. Only very few cases of SVT at MPN diagnosis or previously presented a VAF ≥ 50%, which is very different from MPN without SVT. MPN with evolutive SVT showed the highest JAK2 allele VAF. Abbreviation: VAF, variant allele frequency; MPN, myeloproliferative neoplasm; SVT, splanchnic vein thrombosis
