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. 2024 Jan 24;103(3):737–747. doi: 10.1007/s00277-023-05610-x

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Fig. 5 — Disease progression according to molecular risk in 255 MPN patients. Kaplan-Meier estimates of disease progression at 20 years was 51% and 8% in patients classified as high and low molecular risk, respectively (p < 0.0001). Molecular high-risk (red line) included patients with TP53, chromatin/spliceosome, or homozygous JAK2 mutation (n = 71). Molecular low-risk (blue line) included patients with heterozygous JAK2 mutation (n = 184). Abbreviation: MPN, myeloproliferative neoplasm; SVT, splanchnic vein thrombosis