Table 1.
Baseline characteristics of the study cohort.
| Variable | Full Analysis Set (n = 50) |
|---|---|
| Age (years) | 47.6 (14.1) 49.5 (22–73) |
| Female sex | 25 (50%) |
| Diabetes duration (years) | 25.4 (12.9) 25 (2–54) |
| Haemoglobin A1c (mmol/mol) | 68.8 (10.8) 65 (58–105) |
| Haemoglobin A1c (%) | 8.44 (0.99) 8.1 (7.5–11.8) |
| Weight (kg) | 86.8 (17.3) 83 (60–130) |
| Body mass index (kg/m2) | 29.2 (5.2) 28.9 (20.1–47.8) |
| Smoking | 5 (10%) |
| CGM mean (mmol/L)a | 9.2 (2.1) 9.0 (4.5–14.1) |
| Percent time in range 3.9–10 mmol/La | 53.1 (15.6) 49.4 (22.8–81.2) |
| Percent time above range >10 mmol/La | 38.7 (19.5) 37.7 (4.4–77.2) |
| Percent time in hyperglycaemia >13.9 mmol/La | 13.8 (11.8) 13.2 (0–46.1) |
| Percent time in hypoglycaemia <3.0 mmol/La | 3.33 (4.66) 1.62 (0–20.2) |
| Percent time below range <3.9 mmol/La | 8.2 (8.96) 5.1 (0–44.8) |
| Systolic blood pressure (mmHg) | 134.1 (14.5) 133 (90–163) |
| Diastolic blood pressure (mmHg) | 74.8 (9.6) 75.5 (55–103) |
| Total cholesterol (mmol/L) | 4.14 (0.78) 4.2 (2.7–6.1) |
| Low-density lipoprotein (mmol/L) | 2.31 (0.70) 2.1 (1–4.1) |
| High-density lipoprotein (mmol/L) | 1.46 (0.43) 1.4 (0.7–2.6) |
| Triglycerides (mmol/L) | 1.17 (0.62) 0.98 (0.4–2.8) |
| Insulin pump | 17 (34%) |
| Total daily insulin dose (IU)b | 58.6 (36.4) 47.5 (23.9–206) |
| Daily mealtime (bolus) insulin (IU)b | 23.7 (17.9) 17.8 (5.8–91) |
| Daily basal insulin (IU)b | 33.8 (21.3) 26 (11–136) |
| Total daily insulin dose (IU)b | 58.6 (36.4) 47.5 (23.9–206) |
Data are presented as mean (standard deviation), median (minimum–maximum value) for numeric variables and as numbers and percentages for categorical variables.
a
CGM data available at baseline available for 36 individuals.
b
Data on insulin available for 45 individuals.