Table 5.

Comparisons of no OAC, Warfarin and DOAC in patients with AF aged ≥80 years.¹²³

Outcome	Comparison
	DOAC vs. no OAC		Warfarin vs. no OAC		DOAC vs. Warfarin
	HR	95% CI	HR	95% CI	HR	95% CI
Dementia	0.68	0.65–0.71	0.76	0.73–0.79	0.90	0.86–0.93
All-cause mortality	0.49	0.48–0.50	0.67	0.66–0.68	0.74	0.72–0.76
Ischaemic stroke	0.87	0.83–0.91	0.99	0.95–1.04	0.86	0.82–0.90
Major bleeding	1.08	1.05–1.11	1.05	1.03–1.07	0.88	0.85–0.90

DOAC, direct oral anticoagulant; OAC, Oral anticoagulant; HR, Hazard Ratio; CI, Confidence Interval.