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. 2024 Feb 14;35(1):13. doi: 10.1007/s10856-024-06781-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — A–L Photomicrographs showing portions of sections submitted to immunohistochemistry for detection of OCN (in brown colour) and counterstained with haematoxylin. In BIO (A–D) and CAL (E–H) some elliptical and/or fusiform cells exhibit immunolabelling in their cytoplasm (arrows). None immunolabelled cell is observed in the CG specimens (I–L). Arrowhead: material particles; BV, blood vessels. Bars: 18 μm. Figure 3M—Graphic showing the number of OCN-immunolabelled cells per mm² (expressed as mean ± standard deviation) from BIO, CAL and CG groups at 7, 15, 30 and 60 days. In each period, the comparison among the groups is indicated by superscript letters; different letters = significant difference. The superscript numbers indicate the analysis of each group over time; different numbers = significant difference. Tukey’s test (p ≤ 0.05)