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. 2024 Feb 14;15:1348. doi: 10.1038/s41467-024-45555-x

Fig. 3. Galunisertib decreases viral reservoir in absence of systemic inflammation.

Fig. 3

A Levels of cell-associated (CA)-vDNA per cell equivalent are shown for the time point before cycle 1 (BC1) and at the end of cycle 3 (AC3) or 4 (AC4) for the respective tissues for all 8 macaques. B IPDA data are shown for intact and total provirus for BC1 and AC4 in PBMC for the 8 macaques. P-values are shown for Wilcoxon matched pair signed-rank non-parametric two-tailed test comparing before and after galunisertib data from the 8 macaques (*p ≤ 0.05 **p ≤ 0.01 ***p ≤ 0.01). C Heat map of cytokine concentration in plasma at the indicated time point are shown after Log transformation and normalization. Statistical analysis was run on each factor separately and together (no significant differences after multiple comparison adjustment). Source data are provided as a Source Data file.