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Effects of thioglycolate (TG) pretreatment on circulating TNF-α (A) or IL-6 (B) levels induced by LPS in d-GalN-sensitized mice. Mice were treated as described in the text, and cytokine levels in serum collected 1.5 h after R-LPS challenge were determined by ELISA. Cytokine levels in sera collected 4 h after stimulation were below the detection limit. Results from one representative experiment, repeated five times, are depicted.
