TABLE 4.

Immunization with DbpA, but not OspA, protects mice from challenge with blood-borne B. burgdorferi N40

Source of borrelia and day postinoculation or no.	Immunogen	Prevalence of DbpB IgG	Prevalence of infectiona	P value
Blood, day 4	Lpp2:DbpAN40	0/10	1/10	0.0095
	Lpp2:OspAN40	9/10	7/10	0.37
	E. coli extract	NDb	7/10
Blood, day 6	Lpp2:DbpAN40	1/10	1/10	0.0027
	Lpp2:OspAN40	10/10	8/10	0.42
	E. coli extract	9/10	8/10
Culture (104)	Lpp2:DbpAN40	0/5	0/5	0.0040
	Lpp2:OspAN40	4/5	1/5	0.024
	E. coli extract	+c	5/5

^aCumulative results of bladder, tibiotarsal joint, ear tissue, blood, and inoculation site skin cultures. 

^bND, not done. 

^cPooled sera tested.