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Glycosaminoglycan-binding domain on CXCL8 dimer. CXCL8 has three binding domains: a high-affinity binding domain, which mediates binding to specific receptors on polymorphonuclear neutrophils; the glycosaminoglycan-binding domain (K20, R60, K64, K67, R68); and the dimer interface (R6), where CXCL8 molecules bind to each other to form dimers. Blue and red show positively and negatively charged regions, respectively.
