Table 2.
Summary of statistical comparisons of EC50 and Imax values for L-AChR subunit combinations. ACh. Imax is the relative maximal current obtained at saturating agonist concentration.
| L-AChR subunit combination (ligand) EC50 | Statistical significance (p-value) |
|---|---|
| S168 vs S168T (ACh) | p=<0.001 |
| S168 vs S168T (LEV) | p=<0.001 |
| S168 vs S168 + S168T (ACh) | p = 0.048 |
| S168 vs S168 + S168T (LEV) | p = 0.082 |
| L-AChR subunit combination (ligand) Imax | Statistical significance (p-value) |
|---|---|
| S168 vs S168T (ACh) | p = 0.001 |
| S168 vs S168T (LEV) | p=<0.001 |
| S168 vs S168 + S168T (ACh) | p = 0.162 |
| S168 vs S168 + S168T (LEV) | p=<0.001 |