Figure 2.

Exercise and aging regulated the homeostasis of serum metabolites in rats

(A) Venn diagram of metabolites with significant change compared the 63rd day with the 0th day.

(B) PCA of C, A, and AE groups on the fourth 63rd day (confidence interval = 0.9).

(C), (D), and (E) were the volcano plots metabolites in the positive ion model.

(F), (G), and (H) were the volcano plots metabolites in the negative ion model. The horizontal dashed line represents the threshold for p value of 0.05, and the vertical dashed lines represent thresholds for ± 2-fold changes. Both the 63rd day and the 0th day of the three groups were analyzed using paired tests. See also Figure S2.