Figure 6.

Metabolic pathways regulated by aging and exercise

(A) The main class of metabolites.

(B) The KEGG enrichment of metabolites with the same trend between groups C and AE and that was opposite to group A.

(C) The metabolites of glycine serine and threonine metabolism.

(D) Schematic representation of selected metabolism of glycine, serine, and threonine metabolism; cysteine and methionine metabolism; tryptophan metabolism; and vitamin B6 metabolism.

(E) The metabolites of vitamin B6 metabolism.

(F) The metabolites of tryptophan metabolism.

(G) The metabolites of cysteine methionine metabolism (Data of (C), (E), (F), and (G) were represented as median ± interquartile range). See also Figures S6, S7 Tables S2 and S3.