Table 5.

Polosa et al., epidemiological study description and results

Author, year	Study design	Population	Mean Age (SD)	%Men	Nicotine levels	Blood pressure measures	Results for SBP (baseline/1/2/3 years)	Results for DBP (baseline/1/2/3 years)
Polosa, 2017	Prospective cohort (3.5 years follow-up)	Daily e-cig users (n = 9) and never smokers (controls) (n = 12)	e-cig users/controls 26.6 (6.0)/27.8 (5.2) years	66%	0% (n = 3) 0.9–1.2% (n = 4) 1.6–1.8% (n = 2)	2 SBP/DBP measures in seated position after 5 min of rest at baseline and follow-up visits at 1, 2, and 3 years	e-cig 115(9)/116(5)/114(9)/118(10) controls: 117(9)/117(10)/116(10)/116(9) p value effect between groups = 0.82	e-cig: 79(6)/78(4)/73(9)/76(8) controls: 74(9)/76(6)/75(9)/73(9) p value effect between groups = 0.50