Table 1.

MRI characteristic lesion features typical for multiple sclerosis (Polman et al., 2011; Filippi et al., 2019)

Shape	Ovoid/round
Size	Min. 3 mm in long axis; long axis is often perpendicular to the trunk of lateral ventricle
Localization	Periventricular – abutting the lateral ventricles without any gap between them; also lesions in corpus callosum, but not in the deep grey matter structures Cortical/juxtacortical Infratentorial Spinal cord
Gadolinium	Open-ring, closed-ring enhancing