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Effect of the prostaglandin I2 analogues epoprostenol or treprostinil on (A) T regulatory cell (Treg) (Foxp3+CD4+) percentage, (B) Foxp3 mean fluorescence intensity in Tregs, (C) CD44 mean fluorescence intensity in Tregs, and (D) ratio of T effector cells (CD4+Foxp3−) to Tregs (CD4+Foxp3+). Analysis was performed with a paired t test. *P < 0.05. MFI = mean fluorescence intensity; PGI2 = prostaglandin I2.
