TABLE 2.

Meta-Analysis of Regression Coefficients for Biological Sex, IPT, PGS, and Interactions Between them for Alcohol Use Behaviors Based on Fixed Effect Model.

Variable	β	Standard error	p-value	I 2	Cochran’s Q p-value
Alcohol Consumption
Sex
Male	Reference
Female	−0.300	0.061	1.02 x 10−6	35.73	0.183
IPT Exposure
No exposure	Reference
IPT Exposure	0.313	0.084	2.13 × 10 –4	46.39	0.108
Sex by IPT Exposure	0.136	0.104	0.193	0.0008	0.407
PGS
PGS	0.086	0.030	3.97 x 10−3	0.000	0.669
PGS by IPT Exposure	−0.047	0.049	0.333	0.000	0.795
Alcohol Use Disorder
Sex
Male	Reference
Female	0.002	0.012	0.880	57.97	0.049
IPT Exposure
No Exposure	Reference
IPT Exposure	0.110	0.020	3.50 x 10−8	65.75	0.020
Sex by IPT Exposure	0.008	0.024	0.727	30.17	0.220
PGS
PGS	0.019	0.006	1.17 x 10−3	0.000	0.878
PGS by IPT Exposure	−0.008	0.011	0.457	0.000	0.999

Note: IPT, interpersonal trauma; PGS, polygenic score, bolded estimates are significant at p < 0.05.