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. Author manuscript; available in PMC: 2024 Feb 15.
Published in final edited form as: J Pain. 2022 Oct 2;24(2):204–225. doi: 10.1016/j.jpain.2022.08.010

Figure 1.

Figure 1.

DFNS-assessed 3-cluster sensory profiles (Adapted with permission from Baron et al., 2017). Cluster analysis results: Sensory profiles of the 3 clusters presented as mean z scores ± 95% confidence interval for the test data set (n = 902). Positive z scores indicate positive sensory signs (hyperalgesia), whereas negative z values indicate negative sensory signs (hypoesthesia and hypoalgesia). Dashed lines: 95% confidence interval for healthy subjects. Insets show numeric pain ratings for dynamic mechanical allodynia (DMA) on a logarithmic scale (0–100) and frequency of paradoxical heat sensation (PHS; 0–3). Blue symbols: cluster 1 “sensory loss” (42% of sample). Red symbols: cluster 2 “thermal hyperalgesia” (33% of sample). Yellow symbols: cluster 3 “mechanical hyperalgesia” (24% of sample). CDT, cold detection threshold; CPT, cold pain threshold; HPT, heat pain threshold; MDT, mechanical detection threshold; MPS, mechanical pain sensitivity; MPT, mechanical pain threshold; NRS, Numerical Rating Scale; PPT, pressure pain threshold; QST, quantitative sensory testing; TSL, thermal sensory limen; VDT, vibration detection threshold; WDT, warm detection threshold; WUR, wind-up ratio.