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. 2024 Feb 14;44(7):e1528232023. doi: 10.1523/JNEUROSCI.1528-23.2023

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Copyright © 2024 Tseng et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 4. — Optogenetic LC-NA stimulation did not significantly impact behavioral performance on the well-learned lever task. A,B, Percent correct performance did not differ across sexes or LC-NA stimulation groups during the pre-stimulation period (A), nor was percent correct performance altered by LC-NA stimulation (B). C, The number of trials performed per session did not differ across sex or LC-NA stimulation groups during the pre-stimulation period. D, During stimulation, we observed a sex-specific difference in task engagement, but no significant differences across LC-NA treatment groups. ^#p < 0.05, sex effect, two-way ANOVA. E,F, Lever-pressing speed did not differ across sex or LC-NA stimulation group during the pre-treatment period (E) nor did LC-NA stimulation impact pressing speed (F). G, The total number of laser stimulation trains delivered did not differ significantly across LC-NA treatment groups but was higher overall in male rats compared to female rats.