Table 2.
Results of two-way ANOVA testing for effects of sex and LC stimulation frequency on behavior
| Two-way ANOVA | |||
|---|---|---|---|
| psex [Fsex] | pstim [Fstim] | pint [Fint] | |
| Pre-stimulation baseline performance | |||
| Percent correct | 0.668 [0.19] | 0.571 [0.68] | 0.312 [1.26] |
| Trials per session | 0.436 [0.63] | 0.383 [1.06] | 0.931 [0.15] |
| Pressing speed | 0.288 [1.18] | 0.498 [0.82] | 0.056 [2.90] |
| Performance during stimulation | |||
| Percent correct | 0.682 [0.17] | 0.234 [1.52] | 0.115 [2.20] |
| Trials per session | 0.008 [8.21] | 0.360 [1.12] | 0.960 [0.10] |
| Total stimulations | 0.011 [7.58] | 0.599 [0.64] | 0.941 [0.13] |
| Pressing speed | 0.131 [2.45] | 0.789 [0.35] | 0.106 [2.27] |
| Percent change from baseline to treatment period | |||
| Percent correct | 0.341 [0.94] | 0.585 [0.66] | 0.685 [0.50] |
| NumTrials | 0.007 [8.79] | 0.068 [2.71] | 0.710 [0.46] |
| Pressing speed | 0.214 [1.63] | 0.838 [0.28] | 0.243 [1.49] |
During the stimulation period, but not during the pre-stimulation period, a sex-specific effect was observed in the total number of trials performed per session and in the total number of stimulations received. No effects of LC-NA stimulation frequency or sex × stimulation interaction effects were observed for any performance parameter during the pre-stimulation or stimulation periods. Bold denotes statistical significance (p < 0.05).