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. 2024 Jan 4;134(4):e165418. doi: 10.1172/JCI165418

Figure 3. Food intake, energy expenditure, heart rate, and blood pressure responses to MTII.

Figure 3

Food intake following i.p. injection of PBS or MTII in 3-month-old male MC4RF51L and WT mice (n = 5/group) (A) or intra-PVN injection of PBS or MTII in 4- to 5-month-old male MC4RF51L and WT mice (n = 5–6/group) (B). Energy expenditure following i.p. injection of PBS or MTII in 3-month-old male MC4RF51L and WT mice (n = 5–6/group) (C) or intra-PVN injection of PBS or MTII in 4- to 5-month-old male MC4RF51L and WT mice (n = 4–5/group) (D). Heart rate (E) and mean blood pressure (F) after intra-PVN injection of PBS or MTII in 3-month-old female MC4RF51L and WT mice (n = 8–9/group). Data represent mean ± SEM. *P < 0.05, **P < 0.01 vs. WT by 2-way ANOVA.