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. 2024 Feb 2;15:1275064. doi: 10.3389/fimmu.2024.1275064

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Copyright © 2024 Wu, Liu, Zhang, Ye, Gu, Jiang, Zhu, Ye, Li, Huang and Cao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exploring gene expression profiles in pulmonary fibrosis tissue: DEGs identification and functional enrichment analysis. (A) Volcano plot of DEGs (adj.P.Val<0.05, |log2FC|≥1.5) in mRNA expression profiling dataset GSE101286. (B) Volcano plot of DEGs (adj.P.Val<0.05, |log2FC|≥1.5) in dataset GSE110147. (C) Venn diagram depicting the overlapping DEGs, with 94 genes representing the intersection between the GSE101286 and GSE110147 datasets. (D) Bubble chart presenting the Gene Ontology (GO) and pathway enrichment analysis of DEGs in the Microarray analysis. (E) Functional network of enrichment analysis constructed using clusterProfiler. (F) Chord diagram visualizing the functional relationships among the DEGs and GO terms, highlighting the enrichment results from the GEO datasets.